EAVI2020 at HIVR4P
HIV Research for Prevention (HIVR4P) took place virtually in February and many of EAVI2020’s researchers participated in various capacities. HIVR4P is the only global scientific conference focused exclusively on the challenging and fast-growing field of HIV prevention research and to have so many of our researchers involved is a testament to EAVI2020’s commitment to knowledge exchange with its stakeholders and the scientific community. On the HIVR4P programme committee from EAVI2020 includes Dr Gabriella Scarlatti (OSR, Italy), Prof Damien Purcell (UoM, Australia), Prof Rogier Sanders (AMC, The Netherlands), and Prof Robin Shattock (Imperial UK).
Below are just some of the presentations, oral abstracts and co-chairing our EAVI2020 researchers carried out at HIVR4P. The conference programme has more details on all sessions.
EAVI2020 @ HIVR4P
Symposium
B and T cells: Old players, new strategies
Co-chaired by Christian Brander (IrsiCaixa, Barcelona)
Presentation by Gunilla Karlsson Hedestam (Karolinska Institutet, Sweden) – The maturation of B cell responses
Early vaccine clinical studies on native-like envelope trimers and germline-targeting immunogens
Presentation by Katrina Pollock – Native-like trimers based on consensus and mosaic envelope sequences
Getting the job done: Designing immunogens to induce broadly neutralizing antibodies
Co-chairs, Tom Hanke (University of Oxford, UK) and Max Crispin (University of Southampton, UK)
An ambitious and advancing pipeline: T-cell and non-neutralizing antibody-based vaccine strategies
Presentation by Tom Hanke (University of Oxford, UK) – Refocusing T cell responses with therapeutic vaccination strategies
Presentation by Behazine Combadiere (INSERM, CIMI, France) – Innate immune response signatures (adjuvants)
Oral Abstracts
Env and platform designs to improve antibody responses
Co-chaired by Pauline Maisonnasse (Université Paris-Saclay, France)
Presentation by Isabella Huettner (King’s College London, UK) – Cross-reactivity between HIV-1 bnAbs and parasite glycans
Co-chaired by Paul McKay (Imperial College London, UK)
Presentation by Nathifa Moyo (University of Oxford, UK) – Tetravalent immunogen assembled from conserved regions of HIV-1 and delivered as mRNA demonstrates potent preclinical T cell immunogenicity and breadth
Presentation by Eric Arts (Western University, Canada) – A VSV-based HIV-1 vaccine provides protection in macaques against low dose cross-clade SHIVenv_SF162_P3 challenge
Integrating and optimizing cellular responses
Presentation by Narcis Saubi (Vall d’Hebron Institut de Recerca, Barcelona) – BCG.HTI2auxo.int priming vaccination enhances the HIV-1 specific T cell immune responses elicited by MVA.HTI
Co-chaired by Marit van Gils (AMC, The Netherlands)
Roundtable
Coming soon to a clinic near you? The antibody infusion pipeline
Presentation by Marit van Gils (AMC, The Netherlands) – Antibodies against COVID-19
