The Quest for an HIV Vaccine
June 24, 2022
What is it about HIV that makes it so difficult to develop a vaccine against it?
HIV
prevention
What is it about HIV that makes it so difficult to develop a vaccine against it?
“We’ve been trying to develop a vaccine for over 30 years as a field. It still remains one of the biggest biological challenges of the generation.” – Professor Robin Shattock. HIV remains a global health issue. According to UNAIDS, there […]
Catch up on EAVI2020’s panel event: What’s next for an HIV vaccine?
Download the December Special Edition (.pdf) Foreword from Robin In this special issue we celebrate the success of our training programme in HIV vaccinology which has directly supported students in obtaining their PhD degrees. The programme has also supported career […]
For World AIDS Day 2021, the EAVI2020 clinicians and researchers are shedding a light on the EAVI2020 clinical trials that aim to help accelerate the search for an effective HIV vaccine. Every year on 1st December since 1988, World AIDS […]
Hi! I’m the EAVI2020-3Sm trial and I am testing the VAC02 vaccine. VAC02 is an HIV vaccine candidate based on discovery of the immunogenicity of a conserved gp41 peptide, namely W614A-3S, recognized by natural broadly Neutralizing Ab detected in HIV-1 […]
Hi! I am Trial HIV-CORE 0051. I am a phase 1/2a open-label trial to assess the safety and immunogenicity of candidate T-cell vaccines ChAdOx1.HTI and MVA.HTI given sequentially to healthy HIV-1/2 negative adult volunteers at the Jenner Institute, University of […]
Hi, I am EAVI2020 trial BCN03. Our trial takes place at IRSICAIXA with Christian Brander (Principal Investigator, IRSICAIXA) Beatriz Mothe (Principal Investigator, IRSICAIXA), working in collaboration with Rogier Sanders (Principal Investigator, AMC) and Dietmar Katinger (Principal Investigator, POLYMUN). Our trial […]
Hi! I am Trial HIV-CORE 0052; a phase I open-label trial aiming to establish and assess the safety and immunogenicity of candidate T-cell vaccines ChAdOx1.tHIVconsv1 and MVA.tHIVconsv3+MVA.tHIVconsv4 given in combination to healthy volunteers at low risk for HIV-1 infection at […]
Hi! I am trial EAVI2020_01. Here at Imperial College London, both scientists and clinicians are leading my study which is modelling the interaction between rationally designed synthetic model viral protein immunogens (EAVI2020_01). We are studying immune responses to several different […]
We revisit some of the early career researchers from our past Students in Focus to see where they are now and how their EAVI2020 experiences have helped them along the way. We continue to be very proud and celebrate the […]
Download the July 2021 newsletter here (.pdf) In this issue: The EAVI2020 team at Oxford begin clinical trial of novel T cell-based HIV vaccine Publications with EAVI2020 Nathifa and Luis with New Investigator awards at HIVR4P Students in Focus […]
We revisit some of our past Students in Focus to see where they are now and how their EAVI2020 experiences have helped them along the way. We continue to be very proud and celebrate the successes of the early career […]
The new trial will evaluate the HIVconsvX vaccine – a mosaic vaccine targeting a broad range of HIV-1 variants, making it potentially applicable for HIV strains in any geographical region. On 5 July, the EAVI2020 team at University of […]
Following a challenging year in the face of the COVID-19 pandemic the consortium is excited to be progressing again at full speed. Read the full EAVI2020 April 2021 newsletter here.
Hello everybody. I’m Narcís Saubi. I’m a chemist, and proud of it. I studied chemistry in Girona and specialized in Biochemistry at Universitat Autonoma de Barcelona. I performed a Masters in Biochemistry, and a research dissertation on Alcohol Dehydrogenase in rat’s eyes […]
HIV Research for Prevention (HIVR4P) took place virtually in February and many of EAVI2020’s researchers participated in various capacities. HIVR4P is the only global scientific conference focused exclusively on the challenging and fast-growing field of HIV prevention research and to […]
As new light springs at the horizon with the rollout of efficacious COVID-19 vaccines, EAVI2020 has received a 12-month extension and its clinical studies across Europe are resuming. A new year, and a very different landscape from the last. EAVI2020 […]
Our partners at CEA in the Infectious Disease Models and Innovative Therapies department (IDMIT) have a post-doc opportunity on a SARS-CoV-2 vaccination project with the Bill & Melinda Gates Foundation. This amazing opportunity is available immediately. Funded for 2 years […]
EAVI2020 Newsletter December 2020 (.pdf opens in a new window) 2020 has been a bumpy ride (to say the least) for everyone, including EAVI2020. Clinical trials had to come to a standstill due to lockdown restrictions and as a result, […]
My name is Alessandra Gallinaro and I am a Postdoc Researcher at the Istituto Superiore di Sanità (ISS) in Rome, Italy. The road to my PhD Whilst studying Medical Biotechnology at “La Sapienza” University in Rome I was captivated by […]
Time to meet: Dominik Damm Where I started I wished to work in the field of HIV vaccine research since I was 13 years old. When I started my study of biology at the University of Regensburg, I tried to […]
The EAVI2020 consortium smiled for a group shot. They met over two full mornings in November. Members presented work-package updates and future work. After four years of 80+ consortium members meeting together every year, this year was the first time […]
Postponed due to the global pandemic, ‘HIV glycoprotein engineering for vaccines’ will be virtual course as organised by EAVI2020 partners, Amsterdam University Medical Centre (AMC). After a few months delay due to COVID-19, EAVI2020 are pleased to announce that the […]
Download the August 2020 newsletter (.pdf). In this issue: EAVI2020 project extension HIVR4P 2021 goes virtual Students in focus: Isabella Huettner & Ehsan Suleiman EAVI2020 out and about Upcoming HIV/AIDS events Other news
Time to meet: Ehsan Suleiman I am an employee of Polymun Scientific and a PhD student of Biomolecular Technology of Proteins (BioToP) at the University of Natural Resources and Life Sciences in Vienna, Austria. I have been involved in the […]
Prof Hanke, EAVI2020 PI at the University of Oxford spoke to Scientia which included his work on T cell response to second-generation conserved immunogen, HIVconsvX, and its predecessor, HIVconsv. Scientia is a popularised outreach journal that provides researchers with a […]
Time to meet: Isabella Huettner During the 4 years of my PhD with Dr Katie Doores at King’s College London (UK), I had the opportunity to attend yearly consortium meetings and several PhD training courses. We are interested in studying […]
Funding body, European Commission recognises blight of COVID-19 on Horizon2020 clinical research COVID-19 has had a considerable impact on the progress of EAVI2020’s clinical trial and lab work. Like many Horizon2020 projects involved in clinical trials, it was required to […]
Download the May 2020 newsletter (.pdf) As the world has been gripped by the COVID-19 pandemic researchers across the EAVI2020 project have responded by providing their experience and technology in the fight against this new viral threat. EAVI2020 clinical trials […]
Read the EAVI2020 Newsletter February 2020 (.pdf) In this issue Project update: mosaic trial commences 9th PhD training course announced Students in focus: Yoann Aldon and Athina Kilpeläinen Upcoming events EAVI2020 publications
Let’s meet Philipp Mundsperger. Hi! My name is Philipp and I am a PhD student at Polymun Scientific and the University of Natural Resources and Life Sciences in Vienna, Austria. Within the scope of the EAVI2020 framework, I am found […]
It’s that time again to shine a light on EAVI2020’s students. So put up your feet, turn off the barrage of incoming COVID-19 news and let’s meet Nathifa Moyo. Written by Nathifa Moyo My research within EAVI2020 is based at […]
The development of an HIV vaccine in photos exhibits at the CSOPA Science Centre, Budapest Hungary. The EAVI2020 photo exhibition, which illustrates the journey of developing an HIV vaccine through powerful images, continues its journey around Europe. The 20 plus […]
Led by Professor Robin Shattock at Imperial College London, the mosaic trial is one of a series of clinical trials as part of the EAVI2020 clinical studies. It will test the immune response to the most vulnerable parts of the […]
Throughout the past four years, the students of EAVI2020 have worked tirelessly in The Continuing Education & Training in HIV vaccine development programme. This is a work package of the EAVI2020 project dedicated to the employment and training of young […]
Feature image by Nino Carè from Pixabay Throughout the past four years, the students of EAVI2020 have worked tirelessly in the Continuing Education & Training in HIV vaccine development programme. This is a work package of the EAVI2020 project dedicated […]
Image by Michael Jarmoluk from Pixabay The 9th PhD course as part of this programme will take place in Amsterdam from 7-8 April 2020. Titled HIV antibody and glycoprotein engineering for therapeutics and vaccines, the course will be co-organised by EAVI2020 […]
UPDATE: this event has been cancelled Organised by EAVI2020’s very own researcher, Prof Rogier Sanders the HIV Vaccine symposium is taking place in March 2020, Keystone USA. Prof Robin Shattock, coordinator of EAVI2020 will be speaking and focussing on vaccine […]
HIV continues to be a major global public health issue, having claimed more than 32 million lives so far (WHO). In the lead up to World AIDS Day 2019, EAVI2020 researchers reminded us of the necessity for an effective HIV […]
Read the EAVI2020 Newsletter November 2019 (.pdf) In this issue: Forward from Prof. Robin Shattock 2nd B-cell trial underway Watch later: EAVI2020 webinar – Developing an effective HIV vaccine: what do we need and when will we get there? EAVI2020 […]
First attempts to develop a vaccine against HIV started in the 1980s. Thirty years on and we still do not have a viable vaccine. Why has it been so difficult? What is needed to realise the goal of an effective […]
EAVI2020 was well represented at Cent Gardes Symposium. Organised by the Mérieux Foundation, the forum of international experts took place from 30 September to 2 October in France. Partners, Imperial College London, CEA and AMC were in good company in […]
In this issue, we have more information about the upcoming EAVI2020 webinar titled ‘DEVELOPING AN EFFECTIVE HIV VACCINE: What do we need and when will we get there?’. Download the EAVI2020 Newsletter Autumn Issue 2019 (.pdf)
It’s time to take a look at one of EAVI2020’s partners, Fundació Privada Institut de Recerca de la Sida-Caixa (IrsiCaixa) situated in Barcelona, Spain. We had a quick chat with Dr Christian Brander leading the research at IrsiCaixa to learn […]
EAVI2020 coordinator, Prof Robin Shattock lead the recent Imperial Global Science Policy Forum which focussed on global challenges surrounding vaccines and the latest research in vaccine technology. EAVI coordinator, Prof Robin Shattock presented at the recent Imperial Global Science Policy […]
The EAVI2020 Newsletter May 2019 is here! This issue features the start of clinical trials for HIV vaccine as well as the 7th PhD Training Course in Vienna.
Dr. Joan Joseph from Fundació Privada Clínic per a la Recerca Biomèdica (FCRB) and Prof. Brita Wahren from the Karolinska Institutet have recently returned from the hugely successful 7th PhD training course, “From Lab to Clinic”. It was held 7-10 […]
The European AIDS Vaccine Initiative (EAVI2020) are getting closer to developing a protective vaccine against HIV with clinical trials now underway. Researchers are excited to announce they have started clinical trials to develop a protective vaccine against HIV. This is […]
The EAVI2020 Newsletter February 2019 is here! This month’s newsletter features our project Partner IAVI-HIL as well as the 7th PhD Training Course and upcoming events.
A TRANSVAC Workshop entitled ‘In vivo imaging of host response to vaccines and infections’ will be taking place in Fontenay-aux-Roses, France on the 29th March 2019. Led by our Partner institution CEA, the aim of this workshop is to present and discuss […]
The EAVI2020 Newsletter November 2018 is here! This month’s newsletter provides insight into our 3rd Annual Meeting, including the 6th PhD Training Course, as well as highlights from HIVR4P and the EAVI2020 Photo Exhibition.
Our Consortium members are delighted to have been given the opportunity to host a Satellite Session at this year’s HIVR4P Conference taking place in Madrid, Spain. This is a prestigious event which attracts international recognition from leaders in the field […]
‘The Development of an HIV Vaccine in Photos’ was most recently held at INSERM and has now moved to another one of our project Partners, CEA also based in Paris, France. The exhibition is on display in the cafeteria in CEA […]
The EAVI2020 Newsletter August 2018 is here! This month’s newsletter provides exciting updates of our EAVI2020’s Prof. Stephen Kent who embarked on his European tour, a feature on our project Partner Karolinska Institutet (KI) and updates on all our upcoming events. […]
Situated centrally in Stockholm, Karolinska Institutet (KI) has been committed to medical research and education for over 200 years. Immunology has always been a strong discipline at KI, spanning both experimental and clinical research. A hallmark of KI is that […]
Prof Stephen Kent and Prof Robin Shattock outside the entrance to St Mary’s Hospital, Imperial College London Established in 1853, the University of Melbourne (UOM) is an internationally recognised institution that makes distinctive contributions to society in research, learning and […]
The EAVI2020 Newsletter May 2018 is here! This month’s newsletter provides exciting updates of our EAVI2020’s Photo Exhibition which is on display in Paris, our project Partner AMC and highlights from past and upcoming events.
After the success of ‘The Development of an HIV Vaccine in Photos’ exhibition held in Hospital Clínic, Barcelona, we’re thrilled to announce that the exhibition will now be displayed by our Partner institute INSERM (CIMI-Paris). The exhibition will commence on […]
EAVI2020 is a collaborative research project that aims to accelerate the identification and development of an effective HIV vaccine that may have utility both to prevent infection and contribute to the establishment of long-term remission in those infected with the virus. Since its […]
Professor Rogier Sanders (Principal Investigator) and Assistant Professor Marit van Gils of Academisch Medisch Centrum (AMC) were recently featured in a children’s program broadcast on Dutch national television. “De Buitendienst” is an educational program aimed at children aged 9-12. The […]
The February 2018 EAVI2020 Newsletter is here! This month’s newsletter provides an exciting insight into EAVI2020’s publications for 2017, our project Partner Polymun and highlights from past and upcoming events.
Founded in 1992, Polymun is a private company fully owned by the Katinger family, located in Klosterneuburg. The company offers development and GMP (Good Manufacturing Practice) production of biopharmaceuticals and liposomal formulations of active pharmaceutical ingredients (API) as well as […]
Following on from the success of EAVI20202’s Photo Exhibition launch which was held at Bacanal Café, Barcelona on the 7th November 2017, we have created a brochure that is now available to the general public. The development of the HIV […]
The November 2017 EAVI2020 Newsletter is here! To mark World AIDS Day, this new edition features discussions from our Year 2 Consortium Annual Meeting, the 4th PhD course on HIV immunology and vaccines and a special Photo Exhibition for members of the public, […]
Aprovechando que las 22 instituciones de EAVI2020 estarán en Barcelona para nuestra reunión anual, hemos organizado una exposición de fotos sobre El desarrollo de una vacuna del VIH en fotos en Barcelona, el día 7 Noviembre 2017 de 18:30-20:30 en Bacanal […]
Taking the opportunity that all the partner institutions will be in Barcelona for the project’s annual meeting, EAVI2020 has organised a photo exhibition on The development of an HIV vaccine in Barcelona, 7th November 2017 from 18:30-20:30 at Bacanal Café. […]
EAVI2020’s partner institutions presented the latest research on HIV vaccines at the 9th IAS Conference on HIV Science. The Conference The IAS Conference on HIV Science is the largest open scientific conference on HIV/AIDS. This year was its 9th edition […]
The eAccess Meetings project In 2016, The Global HIV Vaccine Enterprise and Keystone Symposia inaugurated a collaboration to produce an ePanel discussion and series of SciTalks presentations that brought together key experts in the HIV prevention vaccine field. Following the great response […]
The June 2017 EAVI2020 Newsletter is here! This new edition features our Third PhD course on HIV immunology and vaccines, which took place on 23-26 April 2017 in Stockholm. Find out about the exciting topics that were discussed and the students’ opinions on […]
On 23-26 April 2017, EAVI2020 celebrated its Third PhD course on HIV immunology and vaccines. The course was organised by project partners Karolinska Institutet and Fundació Clinic per a la Recerca Biomèdica and took place at Karolinska Institutet, Stockholm. The topics that […]
EAVI2020’s partner institutions presented the latest research on HIV vaccines at the Keystone Symposia on HIV vaccines. As part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation, the HIV vaccines series took place […]
The Beijerinck Premium is intended to encourage virology research and is awarded every two years. Marit van Gils is a post-doc researcher at Academisch Medisch Centrum and is part of the team working in EAVI2020. This award is given to […]
We are excited to present the fifth issue of the EAVI2020 Newsletter! In this issue you will find out about: EAVI2020’s published papers on year 1 Links to talks by EAVI2020 at the 2016 Keystone Symposia on HIV Vaccines Prof Shattock’s […]
The Global HIV Vaccine Enterprise in collaboration with Keystone Symposia organized an ePanel discussion and series of SciTalks presentations that brought together key experts in the HIV prevention vaccine field. The ePanel and SciTalks addressed a broad range of topics […]
Prof Robin Shattock (Imperial) presented at the plenary session of the Spanish AIDS society (GESIDA)’ s AIDS Research Network (RIS) annual meeting in San Sebastian, Spain, 30th November 2016. Prof Shattock was also interviewed by GESIDA on his work on Neutralizing […]
Fundació Clínic per a la Recerca Biomèdica and Karolinska Institutet organised the Second course on HIV immunology and vaccines in Barcelona, 9th November 2016. Twenty four students from all over Europe joined this advanced training session on HIV immunology and vaccines for top […]
17-21 November 2016 Dr Joan Joseph from Fundació Clínic per a la Recerca Biomèdica presented lessons learned on “Pre-clinical development of recombinant BCG based HIV vaccine” at the event, which took place at the Mechninov´s Institute of Vaccine and Sera in Moscow from […]
Coinciding with the project’s one year anniversary, we are excited to publish the fourth issue of the EAVI2020 Newsletter! In this issue we have covered our upcoming EAVI2020 first annual meeting and 2nd PhD course on HIV vaccines and immunology. You […]
The Center for Immunology and Microbial Infection (CIMI-Paris) is a research unit of Inserm – Institut National de Santé et de Recherche Médicale (French National Institutes of Health). At CIMI-Paris and within the EAVI2020 program Behazine Combadière (Director of research, […]
EAVI2020’s partner institutions will be at the HIVR4P Conference in Chicago this week. HIV Research for Prevention 2016: AIDS Vaccine, Microbicide, and ARV-based Prevention Science (HIVR4P 2016) will be held 17–21 October 2016 in Chicago, USA. HIVR4P is the world’s […]
Marit van Gils, who is part of the Academisch Medisch Centrum‘s team involved in EAVI2020, has been selected as one of eight New Investigator Award recipients of the HIV Research for Prevention 2016: AIDS Vaccine, Microbicide and ARV-based Prevention Science […]
Prof José (Pepe) Alcami is the director of the AIDS Immunopathogenesis Unit at Instituto de Salud Carlos III and Coordinator of the Spanish AIDS Research Network (RIS). The AIDS Immunopathogenesis Unit The AIDS Immunopathogenesis Unit works in different projects focused […]
Prof Quentin Sattentau’s lab is one of the groups at the University of Oxford working on the EAVI2020 project. Their work focuses on the function of HIV-1 Env and HIV-1 neutralizing antibodies. Background on the function of HIV-1 Env and […]
The 8th edition of the ICAR (Italian Conference on AIDS and Antiviral Research) will be held in Milan, at University of Milano-Bicocca, from June 6-8, 2016. EAVI2020 partner Ospedale San Raffaele (OSR) will present a paper on neutralizing antibody responses […]
The May issue of the EAVI2020 Newsletter has been published! In this issue, we have covered the most recent project events and news. You can also find links to international press articles about EAVI2020 and a list of upcoming events […]
As part of the EAVI2020 Continuing Education and Training in an HIV vaccine development Programme, project partners Fundació Clinic per a la Recerca Biomèdica and Karolinska Institutet have organized the first training course for PhD students. This course, focused on […]
The first EAVI2020 Newsletter was recently launched! This issue of the project’s Newsletter features three short articles on the first activities of the project since its kick-off date on 1st November 2015. It also includes links to international press articles about EAVI2020 and a list […]
The Neutralizing Antibody Consortium (NAC) held its Annual meeting in La Jolla, California, on the 16th to 18th February 2016. The NAC was launched by EAVI2020’s project partner IAVI in 2002 to solve a fundamental problem in HIV vaccine development: […]
Imperial College hosted EAVI2020 ‘s kick-off meeting in London on Thursday 26th November 2015. Representatives from the project’s partner institutions travelled to London to attend the kick-off meeting of this exciting new initiative, which aims to develop HIV vaccine candidates […]
In response to circa 2 billion euros of Health and ICT innovation-based funding about to be launched by the European Commission, Vision 2020: The Horizon Network hosted London’s Horizon 2020 Health-Tech event on 29 and 30 October 2015. The Health-Tech […]
A new 23 million euro initiative to accelerate the search for an effective HIV vaccine begins today. Financed by the European Commission, the European AIDS Vaccine Initiative (EAVI2020) brings together leading HIV researchers from public organisations and biotech companies from […]