Publications
Publications
The EAVI2020 project resulted so far in the following publications:
- Wee, E.G., Moyo, N.A., Saunders. K. O., LaBranche. C., Donati, F., Capucci. S., Parks, R., Borthwick, N., Hannoun, Z., Montefiori, D.C., Haynes, B.F., Hanke, T. (2019). Parallel induction of CH505 B-cell ontogeny-guided neutralizing antibodies and tHIVconsvX conserved mosaic-specific T cells against HIV. Molecular Therapy – Methods & Clinical Development. Vol 14, September 13, pp 148-160. DOI: 10.1016/j.omtm.2019.06.003
- Vieillard, V., Combadière, B., Tubiana, R., Launay, O., Pialoux, G., Cotte, L., Girard, PM., Simon, A., Dudoit, Y., Reynes, J., Rockstroh, J., Garcia, F., Gatell, J., Devidas, A., Yazdanpanah, Y., Weiss, L., Fätkenheuer, G., Autran, B., Joyeux, D., Gharakhanian, S., Debré, P., Katlama, C. (2019). HIV therapeutic vaccine enhances non-exhausted CD4+ T cells in a randomized phase 2 trial. npj Vaccines Volume 4(25). DOI: 10.1038/s41541-019-0117-5
- Rosás-Umbert, M., Llano, A., Bellido, R., Olvera, A., Ruiz-Riol, M., Rocafort, M., Fernández, M.A., Cobarsi, P., Crespo, M., Dorrell, L., del Romero, J., Alcami, J., Paredes, R., Brander, C., Mothe, B. (2019). Mechanisms of Abrupt Loss of Virus Control in a Cohort of Previous HIV Controllers. Journal of Virology, volume 93 (4) e01436-18; DOI: 10.1128/JVI.01436-18
- Beltran-Pavez, C., Ferreira, C.B., Merino-Mansilla, A., Fabra-Garcia, A., Casadella, M., Noguera-Julian, M., Paredes, R., Olvera, A., Haro, I., Brander, C., Garcia, F., Gatell, J.M., Yuste, E., Sanchez-Merino, V. (2018) Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant. PLoS ONE. Volume 13(12): e0208345. December 19. DOI: 10.1371/journal.pone.0208345
- Yuan, M., Cottrell, C.A., Ozorowski, G., van Gils, M.J., Kumar, S., Wu, N.C., Sarkar, A., Torres, J.L. Val, N., Copps, J., Moore, J.P., Sanders, R.W., Ward, A.B., Wilson, I.A. (2019). Conformational plasticity in the HIV-1 fusion peptide facilitates recognition by broadly neutralizing antibodies. Cell Host & Microbe. Volume 25(6), June 12, Pages 873-883.e5. DOI: 10.1016/j.chom.2019.04.011
- Brouwer, P.J.M., Antanasijevic, A., Berndsen, Z., Yasmeen, A., Fiala, B., Bijl, T.P.L., Bontjer, I., Bale, J.B., Sheffler, W., Allen, J.D., Schorcht, A., Burger, J.A., Camacho, M., Ellis, D., Cottrell, C.A., Behrens, AJ., Catalano, M., del Moral-Sánchez, I., Ketas, T.J., LaBranche, C., van Gils, M.J., Sliepen, K., Stewart, L.J., Crispin, M., Montefiori, D.C., Baker, D., Moore, J.P., Klasse, P.J., Ward, A.B., King, N.P., Sanders, R.W. (2019). Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle. Nature Communications. Volume 10 (4272). September 19. DOI: 10.1038/s41467-019-12080-1
- Torrents de la Peña, A., Rantalainen, K., Cottrell, C.A., Allen, J.D., van Gils, M.J., Torres, J.L., Crispin, M., Sanders, R.W., Ward, A.B. (2019). Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics. PLoS Pathogens. Volume 15(7). July 15. DOI: 10.1371/journal.ppat.1007920
- Borthwick N, Lin Z, Akahoshi T, Llano A, Silva-Arrieta S, Ahmed T, Dorrell L, Brander C, Murakoshi H, Takiguchi M, and Hanke T. (2017). Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines. PLoS ONE 12(4). DOI: 10.1371/journal.pone.0176418
- Ruiz-Riol D, Berdnik A, Llano B, Mothe C, Gálvez S, Pérez-Álvarez B, Oriol-Tordera A, Olvera S, Silva-Arrieta M, Meulbroek F, Pujol J, Coll J, Martinez-Picado C, Ganoza J, Sanchez G, Gómez T, Wyss-Coray C, and Brander C (2017). Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control. Journey of Virology 91(16). DOI: 10.1128/JVI.00441-17
- Capucci S, Wee EG, Schiffner T, LaBranche CC, Borthwick N, Cupo A, Dodd J, Dean H, Sattentau Q, Montefiori D, Klasse P.J, Sanders R.W, Moore J.P, and Hanke T. (2017). HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers. PLoS ONE 12(8). DOI: 10.1371/journal.pone.0181886
- Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye S.W., Moral-Sanchez I.D., McGuire A.T, Yasmeen A, Behrens A, Ozorowski G, van den Kerkhof T.L.G.M., Freund N.T, Dosenovic P, Hua Y, Gitlin A.D., Cupo A, van der Woude P, Golabek M, Sliepen K, Blane T, Kootstra N, van Breemen M.J., Pritchard L.K., Stanfield r.L., Crispin. M, Ward A.B., Stamatatos L, Klasse P.J., Moore J.P, Nemazee D, Nussenzweig M.C, Wilson I.A, and Sanders R.W. (2017). Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. Journal of Experimental Medicine 214(9) DOI: 10.1084/jem.20161160
- van Gils M.J., van den Kerkhof T.L., Ozorowski G, Cottrell C.A., Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye S.W., Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang C.H., Landais E, Nie X, Pritchard L.K., Crispin M, Kelsoe G, Wilson I.A., Schuitemaker H, Klasse P.J., Moore J.P., Burton D.R., Ward A.B., Sanders R.W. (2016). An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability. Nature Microbiology. 2: 16199. DOI: 10.1038/nmicrobiol.2016.199
- Sanchez-Merino A, Fabra-Garcia N, Gonzalez D, Nicolas A, Merino-Mansilla C, Manzardo J, Ambrosioni A, Schultz A, Meyerhans J. R., Mascola J. M., Gatell J, Alcami J. M., Miro E., and Yuste. (2016). Detection of Broadly Neutralizing Activity within the First Months of HIV-1 Infection. Journal of Virology 90(11). DOI: 10.1128/JVI.00049-16
- Hinkula J, Petkov S, Ljungberg K, Hallengärd D, Bråve A, Isaguliants M, Falkeborn T, Sharma S, Liakina V, Robb M, Eller M, Moss B, Biberfeld G, Sandström E, Nilsson C, Markland K, Blomberg P, and Wahren B. (2017). HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV. Heliyon 3(6). DOI: 10.1016/j.heliyon.2017.e00339
- Kratochvil S, McKay P.F., Kopycinski J.T., Bishop C, Hayes P.J., Muir L, Pinder C.L., Cizmeci D, King D, Aldon Y, Wines B.D., Hogarth M, Chung A.W., Kent S.J., Held K, Geldmacher C, Dally L, Santos N.S., Cole T, Gilmour J, Fidler S, and Shattock R.J. (2017). A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens. Frontiers in Immunology 8: DOI: 10.3389/fimmu.2017.00595.
- Stenler K. E., Lundin L, Hansen S, Petkov N, Mozafari M, Isaguliants P, Blomberg C.I.E, Smith D.M, Goldenberg C.H., Chang K. Ljungberg J. Hinkula, and Wahren B. (2017) Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses. Human Vaccines & Immunotherapeutics 13(12). DOI: 10.1080/21645515.2017.1338546
- Olvera A, Martinez J.P., Casadellà M, Llano A, Rosás M, Mothe B, Ruiz-Riol M, Arsequell G, Valencia Gr, Noguera-Julian M, Paredes R, Meyerhans A, and Brander C. (2018). Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro. Frontiers in Immunology DOI: 10.3389/fimmu.2017.02010
- Schiffner T, Pallesen J, Russell R.A., Dodd J, de Val N, LaBranche C, Montefiori D, Tomaras G.D., Shen X, Harris S.L., Moghaddam A.E., Moghaddam A.E., Kalyuzhniy O, Sanders R.W., McCoy L.E., Moore J.P., Ward A.B., and Sattentau Q.J. (2018). Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins. PLOS Pathogens 14(5). DOI: 10.1371/journal.ppat.1006986
- Aldon Y, McKay P.F., Allen J, Ozorowski G, Felfödiné Lévai R, Tolazzi M, Rogers P, He L, de Val N, Fábián K, Scarlatti G, Zhu J, Ward A.B., Crispin M, and Shattock R.J. (2018). Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers. CelRep 24(12). DOI: 10.1016/j.celrep.2018.08.051
- Cheeseman H.M., Day S, McFarlane L.R., Fleck S, Miller A, Cole T, Sousa-Santos N, Cope A, Cizmeci D, Tolazzi M, Hwekwete E, Hannaman D, Kratochvil S, McKay P.F., Chung A.W., Kent S.J., Cook A, Scarlatti G, Abraham S, Combadiere B, McCormack S, Lewis D.J., and Shattock R.J. (2018). Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine. Human Gene Therapy 29(9). DOI: 10.1089/hum.2018.075
- Viegas E.O., Kroidl A, Munseri P.J., Missanga M, Nilsson C, Tembe N, Bauer A, Joachim A, Joseph S, Mann P, Geldmacher C, Fleck S, Stöhr W, Scarlatti G, Aboud S, Bakari M, Maboko L, Hoelscher M, Wahren B, Robb M.L., Weber J, McCormack S, Biberfeld G, Jani I.V., Sandström E, Lyamuya E, and TaMoVac study group. (2018). Optimizing the immunogenicity of HIV prime-boost DNA-MVA-rgp140/GLA vaccines in a phase II randomized factorial trial design. PLOS ONE 13(11). DOI: 10.1371/journal.pone.0206838
- Broset E, Saubi N, Guitart N, Aguilo N, Uranga S, Kilpeläinen A, Eto Y, Hanke T, Gonzalo-Asensio J, Martín C, and Joseph-Munné J. (2019). MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against Mycobacterium tuberculosis in Mice. Molecular Therapy Methods & Clinical Development DOI: 10.1016/j.omtm.2019.01.014
- Sliepen K, Han B.W., Bontjer I, Mooij P, Garces F, Behrens A, Rantalainen K, Kumar S, Sarkar A, Brouwer P.J.M., Hua Y, Tolazzi M, Schermer E, Torres J.L., Ozorowski G, van der Woude P, de la Peña A.T., van Breemen M.J., Camacho-Sánchez J.M., Burger J.A., Medina-Ramírez. M, González. N, Alcami.J, LaBranche.C, Scarlatti G, van Gils M.J., Crispin M, Montefiori D.C., Ward A.B., Koopman G, Moore J.P., Shattock R.J., Bogers W.M., Wilson I.A., and Sanders. R.W. (2019). Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nature Communications DOI: 10.1038/s41467-019-10262-5
The EAVI2020 project resulted so far in the following publications:
- Wee, E.G., Moyo, N.A., Saunders. K. O., LaBranche. C., Donati, F., Capucci. S., Parks, R., Borthwick, N., Hannoun, Z., Montefiori, D.C., Haynes, B.F., Hanke, T. (2019). Parallel induction of CH505 B-cell ontogeny-guided neutralizing antibodies and tHIVconsvX conserved mosaic-specific T cells against HIV. Molecular Therapy – Methods & Clinical Development. Vol 14, September 13, pp 148-160. DOI: 10.1016/j.omtm.2019.06.003
- Vieillard, V., Combadière, B., Tubiana, R., Launay, O., Pialoux, G., Cotte, L., Girard, PM., Simon, A., Dudoit, Y., Reynes, J., Rockstroh, J., Garcia, F., Gatell, J., Devidas, A., Yazdanpanah, Y., Weiss, L., Fätkenheuer, G., Autran, B., Joyeux, D., Gharakhanian, S., Debré, P., Katlama, C. (2019). HIV therapeutic vaccine enhances non-exhausted CD4+ T cells in a randomized phase 2 trial. npj Vaccines Volume 4(25). DOI: 10.1038/s41541-019-0117-5
- Rosás-Umbert, M., Llano, A., Bellido, R., Olvera, A., Ruiz-Riol, M., Rocafort, M., Fernández, M.A., Cobarsi, P., Crespo, M., Dorrell, L., del Romero, J., Alcami, J., Paredes, R., Brander, C., Mothe, B. (2019). Mechanisms of Abrupt Loss of Virus Control in a Cohort of Previous HIV Controllers. Journal of Virology, volume 93 (4) e01436-18; DOI: 10.1128/JVI.01436-18
- Beltran-Pavez, C., Ferreira, C.B., Merino-Mansilla, A., Fabra-Garcia, A., Casadella, M., Noguera-Julian, M., Paredes, R., Olvera, A., Haro, I., Brander, C., Garcia, F., Gatell, J.M., Yuste, E., Sanchez-Merino, V. (2018) Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant. PLoS ONE. Volume 13(12): e0208345. December 19. DOI: 10.1371/journal.pone.0208345
- Yuan, M., Cottrell, C.A., Ozorowski, G., van Gils, M.J., Kumar, S., Wu, N.C., Sarkar, A., Torres, J.L. Val, N., Copps, J., Moore, J.P., Sanders, R.W., Ward, A.B., Wilson, I.A. (2019). Conformational plasticity in the HIV-1 fusion peptide facilitates recognition by broadly neutralizing antibodies. Cell Host & Microbe. Volume 25(6), June 12, Pages 873-883.e5. DOI: 10.1016/j.chom.2019.04.011
- Brouwer, P.J.M., Antanasijevic, A., Berndsen, Z., Yasmeen, A., Fiala, B., Bijl, T.P.L., Bontjer, I., Bale, J.B., Sheffler, W., Allen, J.D., Schorcht, A., Burger, J.A., Camacho, M., Ellis, D., Cottrell, C.A., Behrens, AJ., Catalano, M., del Moral-Sánchez, I., Ketas, T.J., LaBranche, C., van Gils, M.J., Sliepen, K., Stewart, L.J., Crispin, M., Montefiori, D.C., Baker, D., Moore, J.P., Klasse, P.J., Ward, A.B., King, N.P., Sanders, R.W. (2019). Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle. Nature Communications. Volume 10 (4272). September 19. DOI: 10.1038/s41467-019-12080-1
- Torrents de la Peña, A., Rantalainen, K., Cottrell, C.A., Allen, J.D., van Gils, M.J., Torres, J.L., Crispin, M., Sanders, R.W., Ward, A.B. (2019). Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics. PLoS Pathogens. Volume 15(7). July 15. DOI: 10.1371/journal.ppat.1007920
- Borthwick N, Lin Z, Akahoshi T, Llano A, Silva-Arrieta S, Ahmed T, Dorrell L, Brander C, Murakoshi H, Takiguchi M, and Hanke T. (2017). Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines. PLoS ONE 12(4). DOI: 10.1371/journal.pone.0176418
- Ruiz-Riol D, Berdnik A, Llano B, Mothe C, Gálvez S, Pérez-Álvarez B, Oriol-Tordera A, Olvera S, Silva-Arrieta M, Meulbroek F, Pujol J, Coll J, Martinez-Picado C, Ganoza J, Sanchez G, Gómez T, Wyss-Coray C, and Brander C (2017). Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control. Journey of Virology 91(16). DOI: 10.1128/JVI.00441-17
- Capucci S, Wee EG, Schiffner T, LaBranche CC, Borthwick N, Cupo A, Dodd J, Dean H, Sattentau Q, Montefiori D, Klasse P.J, Sanders R.W, Moore J.P, and Hanke T. (2017). HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers. PLoS ONE 12(8). DOI: 10.1371/journal.pone.0181886
- Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye S.W., Moral-Sanchez I.D., McGuire A.T, Yasmeen A, Behrens A, Ozorowski G, van den Kerkhof T.L.G.M., Freund N.T, Dosenovic P, Hua Y, Gitlin A.D., Cupo A, van der Woude P, Golabek M, Sliepen K, Blane T, Kootstra N, van Breemen M.J., Pritchard L.K., Stanfield r.L., Crispin. M, Ward A.B., Stamatatos L, Klasse P.J., Moore J.P, Nemazee D, Nussenzweig M.C, Wilson I.A, and Sanders R.W. (2017). Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. Journal of Experimental Medicine 214(9) DOI: 10.1084/jem.20161160
- van Gils M.J., van den Kerkhof T.L., Ozorowski G, Cottrell C.A., Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye S.W., Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang C.H., Landais E, Nie X, Pritchard L.K., Crispin M, Kelsoe G, Wilson I.A., Schuitemaker H, Klasse P.J., Moore J.P., Burton D.R., Ward A.B., Sanders R.W. (2016). An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability. Nature Microbiology. 2: 16199. DOI: 10.1038/nmicrobiol.2016.199
- Sanchez-Merino A, Fabra-Garcia N, Gonzalez D, Nicolas A, Merino-Mansilla C, Manzardo J, Ambrosioni A, Schultz A, Meyerhans J. R., Mascola J. M., Gatell J, Alcami J. M., Miro E., and Yuste. (2016). Detection of Broadly Neutralizing Activity within the First Months of HIV-1 Infection. Journal of Virology 90(11). DOI: 10.1128/JVI.00049-16
- Hinkula J, Petkov S, Ljungberg K, Hallengärd D, Bråve A, Isaguliants M, Falkeborn T, Sharma S, Liakina V, Robb M, Eller M, Moss B, Biberfeld G, Sandström E, Nilsson C, Markland K, Blomberg P, and Wahren B. (2017). HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV. Heliyon 3(6). DOI: 10.1016/j.heliyon.2017.e00339
- Kratochvil S, McKay P.F., Kopycinski J.T., Bishop C, Hayes P.J., Muir L, Pinder C.L., Cizmeci D, King D, Aldon Y, Wines B.D., Hogarth M, Chung A.W., Kent S.J., Held K, Geldmacher C, Dally L, Santos N.S., Cole T, Gilmour J, Fidler S, and Shattock R.J. (2017). A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens. Frontiers in Immunology 8: DOI: 10.3389/fimmu.2017.00595.
- Stenler K. E., Lundin L, Hansen S, Petkov N, Mozafari M, Isaguliants P, Blomberg C.I.E, Smith D.M, Goldenberg C.H., Chang K. Ljungberg J. Hinkula, and Wahren B. (2017) Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses. Human Vaccines & Immunotherapeutics 13(12). DOI: 10.1080/21645515.2017.1338546
- Olvera A, Martinez J.P., Casadellà M, Llano A, Rosás M, Mothe B, Ruiz-Riol M, Arsequell G, Valencia Gr, Noguera-Julian M, Paredes R, Meyerhans A, and Brander C. (2018). Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro. Frontiers in Immunology DOI: 10.3389/fimmu.2017.02010
- Schiffner T, Pallesen J, Russell R.A., Dodd J, de Val N, LaBranche C, Montefiori D, Tomaras G.D., Shen X, Harris S.L., Moghaddam A.E., Moghaddam A.E., Kalyuzhniy O, Sanders R.W., McCoy L.E., Moore J.P., Ward A.B., and Sattentau Q.J. (2018). Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins. PLOS Pathogens 14(5). DOI: 10.1371/journal.ppat.1006986
- Aldon Y, McKay P.F., Allen J, Ozorowski G, Felfödiné Lévai R, Tolazzi M, Rogers P, He L, de Val N, Fábián K, Scarlatti G, Zhu J, Ward A.B., Crispin M, and Shattock R.J. (2018). Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers. CelRep 24(12). DOI: 10.1016/j.celrep.2018.08.051
- Cheeseman H.M., Day S, McFarlane L.R., Fleck S, Miller A, Cole T, Sousa-Santos N, Cope A, Cizmeci D, Tolazzi M, Hwekwete E, Hannaman D, Kratochvil S, McKay P.F., Chung A.W., Kent S.J., Cook A, Scarlatti G, Abraham S, Combadiere B, McCormack S, Lewis D.J., and Shattock R.J. (2018). Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine. Human Gene Therapy 29(9). DOI: 10.1089/hum.2018.075
- Viegas E.O., Kroidl A, Munseri P.J., Missanga M, Nilsson C, Tembe N, Bauer A, Joachim A, Joseph S, Mann P, Geldmacher C, Fleck S, Stöhr W, Scarlatti G, Aboud S, Bakari M, Maboko L, Hoelscher M, Wahren B, Robb M.L., Weber J, McCormack S, Biberfeld G, Jani I.V., Sandström E, Lyamuya E, and TaMoVac study group. (2018). Optimizing the immunogenicity of HIV prime-boost DNA-MVA-rgp140/GLA vaccines in a phase II randomized factorial trial design. PLOS ONE 13(11). DOI: 10.1371/journal.pone.0206838
- Broset E, Saubi N, Guitart N, Aguilo N, Uranga S, Kilpeläinen A, Eto Y, Hanke T, Gonzalo-Asensio J, Martín C, and Joseph-Munné J. (2019). MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against Mycobacterium tuberculosis in Mice. Molecular Therapy Methods & Clinical Development DOI: 10.1016/j.omtm.2019.01.014
- Sliepen K, Han B.W., Bontjer I, Mooij P, Garces F, Behrens A, Rantalainen K, Kumar S, Sarkar A, Brouwer P.J.M., Hua Y, Tolazzi M, Schermer E, Torres J.L., Ozorowski G, van der Woude P, de la Peña A.T., van Breemen M.J., Camacho-Sánchez J.M., Burger J.A., Medina-Ramírez. M, González. N, Alcami.J, LaBranche.C, Scarlatti G, van Gils M.J., Crispin M, Montefiori D.C., Ward A.B., Koopman G, Moore J.P., Shattock R.J., Bogers W.M., Wilson I.A., and Sanders. R.W. (2019). Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nature Communications DOI: 10.1038/s41467-019-10262-5